ACEP Monkeypox Field Guide

If monkeypox is confirmed, health departments can order medical countermeasures (antivirals and vaccine) from the Strategic National Stockpile upon receipt of a positive orthopoxvirus test.

Many individuals infected with monkeypox virus have a mild, self-limiting disease course lasting from 2 to 4 weeks in the absence of specific therapy.

However, the prognosis for monkeypox depends on multiple factors such as previous vaccination status, initial health status, concurrent illnesses, and comorbidities among others.