The annual Mattox Vegas Trauma, Critical Care & Acute Care Surgery Conference has become the best attended such course in the world. Word of mouth endorsements have led to this course being oversubscribed the last 10 years, with over 80% of attendees comprised of physicians. In 2020, the pandemic forced us to cancel, but we were the first large live conference to safely meet in 2021. Our faculty are physicians in active practice who continue "in the trenches" day after day, night after night, dealing with the most complex surgical challenges. Each year, new "rising stars" join our seasoned, expert, and familiar faculty. As you visit the Scientific Program section of our web site, you will be impressed that such a stellar faculty has been assembled and how so much practical surgical information has been incorporated into two and one-half days. Past attendees have aptly described the conference content as an, "incredible journey in surgical knowledge, with 'tour guides' whose expertise and personalities make every excursion a uniquely exceptional experience," "Amazingly wonderful, fast paced experience - like drinking water from a fire hose - blew me away!" "No other course like this in the world; can't wait to return next year." In line with the post COVID world, we now offer both "Live in Las Vegas" - an in person activity, as well as an online "On Demand" option that will be available for six months after the conference concludes.